The AHT have recommended that an HWV with idiopathic epilepsy has their genome sequenced for the “Give a dog a genome” project. We now need to identify suitable dogs to submit to the AHT for them to select the ideal dog to sequence.
We need details of as many HWV diagnosed with idiopathic epilepsy as possible to allow us the best chance at finding the ideal “candidates”.
The following statement has been issued by the AHT.
“Epilepsy is a devastating neurological disease which can be simply defined as the tendency to have recurrent seizures. Epilepsy is the most prevalent canine neurological disorder and it was the most commonly reported health concern in the AHT’s Give a Dog a Genome breed health summary. This supports the AHT’s on-going efforts understand the genetics of epilepsy.
Prior to the Give a Dog a Genome project the AHT had been focusing its genetic investigation into canine epilepsy in two breeds; the Italian Spinone and the Border Collie. Sequencing the whole genomes of dogs affected with epilepsy from additional breeds as part of the Give a Dog a Genome project could add a crucial resource to these studies and might lead to better understanding of the possible causes of epilepsy across all of these breeds.
Many different breeds suffer from epilepsy although the age of onset and the type and pattern of seizures can differ between breeds. It is likely to be genetically complex and can affect dogs differently making it a challenge to diagnose, treat and prevent. The term ‘Idiopathic Epilepsy’ means that no underlying cause for the seizures can be identified. All other possible causes of seizures, or other diseases which could look like seizures, need to be excluded before idiopathic epilepsy can be diagnosed. It is essential for our research that we are as certain of the diagnosis as possible before a DNA sample from an affected dog is used for whole genome sequencing.”
If you own a dog diagnosed with idiopathic epilepsy please help us by completing our confidential form here and seeing if your dog may be suitable to be sequenced.
For further details contact firstname.lastname@example.org