Godfrey Card (A 2144) and Geoff Saint (non panel)
Godfrey Card (A 2144) and Geoff Saint (non panel)
Jim Bird (B3501) and Dawn Elrington (non-panel)
Various information is now available free of charge from the Kennel Club Academy Shop. There are breeder education learning resourses, canine genetics and biomechanics and movement.
Further information can be found here: https://www.kcacademy.org.uk/shop/
Breed Judge: Tanya Prior (Fradaikee)
Group Judge: Suzy Roffey (Karidell)
Best in Show Judge: Bill Gray (Sygar)
Online entry closes 7 January 2018
Do you own a HWV? If so are you a member of the HWVA? If the answer to both those questions is yes are you able to spare some time to help organise or attend some events on behalf of the Association during the year?
We have a small and very active Committee and run several events through the year but if some jobs could be spread around a little everyone’s life would be easier. Within the Committee there are Show and Working Sub-Committees and both are always looking for willing volunteers. The Open Show held at the beginning of October and the Championship Show usually held around Easter. The Working Sub-Committee run at least two Field Trials, a Pointing Test and a very popular Working Test in September.
If one of the events is near you and you think you could give a little time on the day please contact the Committee (http://hwva.org.uk/the-hwva/committee/). These events are always popular and great fun but we need help to keep them running. If you are interested in being co-opted on to the sub-committee or are interested in taking up the soon to be vacant Field Trial Secretary position or vacancy on the Committee please contact us. If you own a HWV but are not a member please consider joining as a lot of work is done to promote this fantastic breed and to highlight problems and work with other organisations to solve them. All details are on this website: http://hwva.org.uk/the-hwva/membership/.
The HWVA are producing a yearbook, which will be distributed to members during 2018.
For more information and to book your advert you can either order online using the following link: Online order of advertising in Yearbook. Alternatively you can download a booking form to complete here: Booking form 2017 Yearbook.
I attended the KC Breed Health Symposium on 5 October 2017 on behalf of the HWV. There were 200 registrants for the event. We had a number of brief but interesting lectures with health updates in, some of which I have summised below.
A most engaging, knowledgable speaker, Professor Volk gave us a brief rundown on some points about canine epilepsy which I have tried to summarise below.
There have been several studies on the impact of epilepsy on the dog and owner. These seemed to suggest that the biggest concerns about what would cause an impact on the quality of life of the owner were:
Surprisingly cost wasn’t identified!
They identified that support was important and that this is was beneficial coming from
A key point to note is that Idiopathic Epilepsy isn’t just one disease – there are thousands of reasons why it can happen. It is usual that there are multiple predisposing factors all coming together at the same time to cause a seizure.
Specialists diagnosis of seizures tends to be very variable and often biased towards their expectations in certain breeds. Diagnosis is very subjective.
Cognitive Impairments in Epilepsy
There is evidnce to suggest a decrease in cognitive abilities in dogs with epilepsy. It can also reduce their susceptibility to being trained although positive reinforcement works better.
Every brain has the capacity to have seizures
Different brains have different thresholds to trigger seizures
Treatment is based on changing the seizure threshold.
Study on occurence of seizures in untreated dogs
The important thing to note is that drugs aren’t designed to change this pattern of occurance.
The development of new drugs
In general the new drugs that we are seeing developed now don’t tend to be any more effective in stopping/ reducing seizures, their main benefit is to reduce the side effects associated with them.
RVC have developped an app to monitor seizures: Further details here
Diet trials in epilepsy
There has been a trial to see the effect of adding medium chain fatty acids to a diet.
All in all there is some interesting work being done on canine epilepsy. We won’t be able to eradicate it in one step since there are so many different triggers to the condition but working on the individual triggers we may be able to get somewhere.
One of the most important purposes of studying genetics at the AHT is to find deletrious mutations in DNA that can cause disease.
In 2004 the genome of a boxer named Tasha (Can Farm 1.0) was sequenced as a reference genome for others to compare back to.
DNA mutations are found by comparing the DNA of an affected dog to a reference dog without the disorder. Difference genes in the structure are called “candidate genes” and indicate where the mutation may be. By referencing to a succession of further dogs one by one these candidate genes are narrowed down to a single gene that is causing the mutation. This process assumes that reference dogs aren’t going to have the disease you are looking for.
The Give a Dog a Genome project is sequencing genomes from a mixture of healthy dogs of a breed (where there are no major health concerns) and dogs of other breeds with particular health issues being deemed worthy of further investigation. There are 16 breeds where dogs with Ideopathic epilepsy has been sequenced, 9 with PRA, 7 with hereditary cataract and 4 with osteosarcoma with another 24 with other conditions having been sequenced.
So far the project has already identified:
This is an organisation who are allowing collaboration between specialists to try to enable the using and sharing of data from all sorts of international sources. They focus on the Health, Wellbeing and Welfare of dog breeds.
They are building a database to help share information.
They run an International Dog Health Workshop which will be hosted next time by the Kennel Club in the UK. This will be in 2019.
I hope this brief summary gives you a brief insight into some of what was covered. I have tried to keep the information as concise and accurate as possible, however, I cannot be held responsible for any inaccuracies.
Update from the Kennel Club:
“As you already know, we selected a Hungarian Wirehaired Vizsla with Idiopathic Epilepsy to be whole genome sequenced as part of Give a Dog a Genome (GDG). The sequencing has now been completed by the external laboratory and the data has been made available for us to download.
What happens next?
The amount of data generated for each sample is enormous, around 80-90 Gb. To put that into perspective, data from only 10 dogs will fill up the average modern personal computer, and the processing of the data will use the full capacity of the computer for months. As a result it takes time (about 1 week) and a great deal of computing power to download and process the data so that it is ready for analysis. Once we complete this stage the Hungarian Wirehaired Vizsla Idiopathic Epilepsy data will be ready for further analysis.
The data will be added to the genome bank, and will begin contributing to studies in other breeds immediately. In addition, the data will be made available to other scientists for use in their own studies, and your breed has therefore made a vital contribution to genetic research affecting the welfare of dogs worldwide.
Analysis of the data to attempt to identify any variants that contribute to Idiopathic Epilepsy in Hungarian Wirehaired Vizsla will take far longer. Please be aware that it is entirely possible that we will not be able to identify any variants that contribute to this condition, at all.
You will continue to receive any general GDG updates, but apart from that we will contact you only if there is something specific to the Hungarian Wirehaired Vizsla to report. If you don’t hear from us, it means that we are still in the analysis stage and have not found anything of significance.
I would once again like to thank you and the breed community for participating in Give a Dog a Genome.”